OK, lets look at the taste factor. It depends.
If you have no seasoning or one layer of Crisco for seasoning in your DO and cook an acidic food for hours it will taste like shXX ........cast iron.
My DO which has years of cooking bacon, hamburgers, steaks, stir fry and browning beef for stews, chili, etc. has enough seasoning between the CI and the acidic food that there is no CI flavor transfer. Thus I can make spaghetti sauce, chili, or wine soup for hours without hurting the flavor.
What you can cook, how long you can cook it and when it will start to pick up the CI flavor DEPENDS upon the quality/thickness of your seasoning and the acidity of what you are cooking.
Cooking acidic foods will diminish the quality of the seasoning (read eat), so it needs to be rebuilt before the next round or it will eventually go away.
Hilditch